Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-KIN HPA038700 · Atlas Antibodies	HPA038700 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-RUNX1 HPA037912 · Atlas Antibodies	HPA037912 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-BACH1 HPA034949 · Atlas Antibodies	HPA034949 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZBTB21 HPA031758 · Atlas Antibodies	HPA031758 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-YY2 HPA030335 · Atlas Antibodies	HPA030335 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-EGR1 HPA029938 · Atlas Antibodies	HPA029938 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ETV1 HPA077249 · Atlas Antibodies	HPA077249 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-GATA3 AMAb91525 · Atlas Antibodies	AMAb91525 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-FOXM1 HPA029974 · Atlas Antibodies	HPA029974 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-BRD4 HPA061646 · Atlas Antibodies	HPA061646 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ETV1 HPA077249-25ul · Atlas Antibodies	HPA077249-25ul Atlas Antibodies	25 µl	£228.00 25 µl view
Anti-BRD4 HPA061646-25ul · Atlas Antibodies	HPA061646-25ul Atlas Antibodies	25 µl	£306.00 25 µl view
Anti-FOXM1 HPA029974-25ul · Atlas Antibodies	HPA029974-25ul Atlas Antibodies	25 µl	£306.00 25 µl view
Anti-GATA3 AMAb91525-25ul · Atlas Antibodies	AMAb91525-25ul Atlas Antibodies	25 µl	£245.00 25 µl view

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In this section

Download the ChIP-Exo-Seq application note