- In this section:
- Biosimilar monoclonal antibodies: InVivoSIM
- Cell lines for drug discovery
- Cell line development
- Continuous kinase enzyme & inhibitor activity assays: PhosphoSens
- Gene editing tools for drug discovery
- Lipid nanoparticle research tools for targeted drug delivery
- In vivo antibodies: InVivoMAb and InVivoPlus
- Small molecule drug discovery solutions
- Services for drug discovery
Accelerating drug discovery from target identification to preclinical research
Drug discovery is a complex, multi-stage process that requires robust tools, validated models, and trusted reagents at every step. We provide researchers with access to a comprehensive portfolio of products and technologies that support the complete drug discovery workflow, from early target identification through to preclinical testing.
Working with leading global suppliers, we help scientists generate biological insights, validate therapeutic targets, identify promising compounds, develop screening assays, and evaluate safety and efficacy using advanced model systems.
Explore the stages and our solutions across the drug discovery pipeline below.
The first stage of drug discovery focuses on identifying biological targets that play a role in disease progression. Researchers use genomic, transcriptomic, and proteomic approaches to uncover potential therapeutic targets and biomarkers.
Key applications
- Genomics and transcriptomics
- Biomarker discovery
- Target expression profiling
- Pathway analysis
Our featured solutions
- Zymo Research: nucleic acid extraction kits and NGS sample preparation solutions
- Lexogen: Gene expression and whole transcriptome sequencing solutions
- Active Motif: Epigenetic research tools such as ChIP-seq and chromatin analysis kits
- Atlas Antibodies: Highly validated pathway-specific antibody collections
- RayBiotech: Cytokine and antibody arrays, alongside recombinant proteins for biomarker research
By combining high-quality sample preparation, sequencing technologies, and validated detection tools, researchers can confidently identify and prioritise potential therapeutic targets.
Once a target has been identified, researchers must confirm its biological relevance and therapeutic potential. Target validation studies help establish whether modulation of a target produces the desired effect.
Key applications
- Gene editing and knockdown
- Functional validation
- Mechanism of action studies
- Target engagement analysis
Our featured solutions
- OriGene: Gene knockdown and knockout kits, expression vectors
- Mirus Bio: Transfection reagents and viral delivery systems
- BPS Bioscience: Knockout and overexpression cell lines, target engagement assays, and cell-based assays
- Bio X Cell: In vivo functional antibodies and immune modulation tools
- Bethyl Laboratories: Flow cytometry antibodies, immunohistochemistry reagents, and assay validation tools
- Lucigen: High-efficiency competent cells for molecular biology workflows
These technologies enable researchers to investigate gene function, validate disease mechanisms, and establish confidence in potential therapeutic targets.
Following target validation, researchers screen compounds and disease models to identify molecules that demonstrate biological activity against the target.
Key applications
- Small molecule screening
- Phenotypic screening
- Lead discovery
- Cell-based disease model studies
Our featured solutions
- Cayman Chemical: Bioactive compounds, pathway-focused inhibitors and small molecule libraries
- MedChem Express: Compound screening collections and bioactive molecules
- BPS Bioscience: Reporter cell lines, pathway-specific assays and luciferase assay platforms
- Cytion: Disease-relevant cell lines and cancer research models
- INDIGO Biosciences: reporter assay kits and nuclear receptor assay systems
These tools support the efficient discovery of hit compounds and provide researchers with biologically relevant models for evaluating activity and selectivity.
Promising compounds must be screened and characterised to determine potency, selectivity, and mechanism of action. Reliable assay platforms are essential for generating reproducible data and advancing candidates.
Key applications
- High-throughput screening
- Cell-based screening
- Biochemical assays
Our featured solutions
- BellBrook Labs: High-throughput screening and enzyme activity assays
- BPS Bioscience: Target engagement and biochemical assays
- MedChem Express: Screening compound libraries
- Cell Biolabs: Cell viability and cytotoxicity assays
Our range of screening technologies enables efficient evaluation of compound performance in both biochemical and cellular systems.
Before clinical development, drug candidates undergo extensive testing to evaluate safety, efficacy, pharmacokinetics, and biological response using increasingly complex and physiologically relevant models.
Key applications
- Toxicity screening
- ADME profiling
- Biomarker detection
- Organoid and 3D culture models
Our featured solutions
- RayBiotech: Multiplex ELISA platforms. apoptosis and biomarker assays
- Hycult Biotech: Complement pathway assays and innate immunity research tools
- ZenBio: Primary human cells and specialised cell culture media
- Cytion: Caco-2 and MDCK cell models for ADME studies
- INDIGO Biosciences: ADME and safety screening assays
- abm: Spheroid and organoid medium kits, advanced 3D culture platforms
These solutions help researchers generate more predictive preclinical data and improve confidence in candidate selection before clinical development.
In this section
Biosimilar monoclonal antibodies: InVivoSIM- Cell lines for drug discovery
- Cell line development
- Continuous kinase enzyme & inhibitor activity assays: PhosphoSens
- Gene editing tools for drug discovery
- Lipid nanoparticle research tools for targeted drug delivery
- In vivo antibodies: InVivoMAb and InVivoPlus
- Small molecule drug discovery solutions
- Services for drug discovery