Life science blog

Rapid dysfunction of natural killer cells in tumours and its implications for cancer immunotherapy

Natural killer (NK) cells are key components of the innate immune system, known for their ability to directly kill tumour cells and coordinate broader anti-tumour immune responses. Despite their potent cytotoxic ...
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DNA purity is the foundation for downstream success

DNA extraction is a foundational step in molecular biology workflows, directly influencing the performance and reliability of all downstream analytical applications. Even trace amounts of carryover contaminants can have ...
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Immune resistance in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) ranks among the deadliest malignancies, due in large part to a highly immunosuppressive tumour microenvironment. Although approximately 30% of PDAC tumours express PD L1, immune ...
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Why microbiome standards matter: improving reliability and reproducibility

Modern microbiome research depends heavily on Next-Generation Sequencing (NGS). These methods allow scientists to characterise complex microbial communities in remarkable detail. Despite their power, microbiome analysis ...
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Creating a confident foundation with clean plasmid DNA

Plasmid purification is often assessed using simple spectrophotometric metrics such as the A260/280 ratio, which primarily reflects protein contamination. However, this measurement provides only a narrow view of purity. ...
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The role of functional antibodies in understanding the tumour microenvironment

Functional antibodies have become important tools for investigating the intricate tumour microenvironment (TME) and advancing next generation immunotherapies. Tumours do not exist in isolation; they develop within a ...
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