Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-TERF1 HPA048379 · Atlas Antibodies	HPA048379 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-PCF11 HPA040779 · Atlas Antibodies	HPA040779 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-FOXP2 HPA001679 · Atlas Antibodies	HPA001679 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MYOG HPA028336 · Atlas Antibodies	HPA028336 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-LHX2 HPA000838 · Atlas Antibodies	HPA000838 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-BRD9 HPA023197 · Atlas Antibodies	HPA023197 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-HAND2 HPA019591 · Atlas Antibodies	HPA019591 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NFIX HPA007533 · Atlas Antibodies	HPA007533 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-UBE2B HPA003875 · Atlas Antibodies	HPA003875 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ETS2 HPA003176 · Atlas Antibodies	HPA003176 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TSC22D3 HPA001916 · Atlas Antibodies	HPA001916 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-DMAP1 HPA028419 · Atlas Antibodies	HPA028419 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF232 HPA028611 · Atlas Antibodies	HPA028611 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-USF2 HPA029764 · Atlas Antibodies	HPA029764 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-WDR82 HPA040427 · Atlas Antibodies	HPA040427 Atlas Antibodies	100 µl	£455.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note