Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-ERG HPA046598 · Atlas Antibodies	HPA046598 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF26 HPA042406 · Atlas Antibodies	HPA042406 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-USF1 HPA036233 · Atlas Antibodies	HPA036233 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MED28 HPA035901 · Atlas Antibodies	HPA035901 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SETD5 HPA035574 · Atlas Antibodies	HPA035574 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-STAT3 HPA058603 · Atlas Antibodies	HPA058603 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-ZNF200 HPA059310 · Atlas Antibodies	HPA059310 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-FOSL2 HPA061417 · Atlas Antibodies	HPA061417 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NFAT5 HPA069711 · Atlas Antibodies	HPA069711 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-FOXL2 HPA069613 · Atlas Antibodies	HPA069613 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-DDIT3 HPA068416 · Atlas Antibodies	HPA068416 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-SOX17 HPA068399 · Atlas Antibodies	HPA068399 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TAF6L HPA067239 · Atlas Antibodies	HPA067239 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF383 HPA063945 · Atlas Antibodies	HPA063945 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-JUND HPA063029 · Atlas Antibodies	HPA063029 Atlas Antibodies	100 µl	£429.00 100 µl view

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Download the ChIP-Exo-Seq application note