Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-SIN3A HPA062123 · Atlas Antibodies	HPA062123 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-GTF2B HPA061626 · Atlas Antibodies	HPA061626 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-GTF3C6 HPA061345 · Atlas Antibodies	HPA061345 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-JDP2 HPA059511 · Atlas Antibodies	HPA059511 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF569 HPA052994 · Atlas Antibodies	HPA052994 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-BRD3 HPA051830 · Atlas Antibodies	HPA051830 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF300 HPA051777 · Atlas Antibodies	HPA051777 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-GTF3C1 HPA051617 · Atlas Antibodies	HPA051617 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF281 HPA051228 · Atlas Antibodies	HPA051228 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF524 HPA050981 · Atlas Antibodies	HPA050981 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NFYA HPA050779 · Atlas Antibodies	HPA050779 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF697 HPA049933 · Atlas Antibodies	HPA049933 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POLR2G HPA053000 · Atlas Antibodies	HPA053000 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF394 HPA054639 · Atlas Antibodies	HPA054639 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-DR1 HPA055308 · Atlas Antibodies	HPA055308 Atlas Antibodies	100 µl	£455.00 100 µl view

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Download the ChIP-Exo-Seq application note