Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-KMT2A HPA044910 · Atlas Antibodies	HPA044910 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TP73 HPA044516 · Atlas Antibodies	HPA044516 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-NELFA HPA043931 · Atlas Antibodies	HPA043931 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-INTS12 HPA041814 · Atlas Antibodies	HPA041814 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-INO80 HPA041484 · Atlas Antibodies	HPA041484 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TBX15 HPA052245 · Atlas Antibodies	HPA052245 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SYAP1 HPA048047 · Atlas Antibodies	HPA048047 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-THAP5 HPA051488 · Atlas Antibodies	HPA051488 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-BCL6 HPA050645 · Atlas Antibodies	HPA050645 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-COPS3 HPA050557 · Atlas Antibodies	HPA050557 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF507 HPA049728 · Atlas Antibodies	HPA049728 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZXDC HPA049593 · Atlas Antibodies	HPA049593 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TAF11 HPA049127 · Atlas Antibodies	HPA049127 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-EP400 HPA049013 · Atlas Antibodies	HPA049013 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF317 HPA048625 · Atlas Antibodies	HPA048625 Atlas Antibodies	100 µl	£455.00 100 µl view

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Download the ChIP-Exo-Seq application note