Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-ZFHX3 HPA059353 · Atlas Antibodies	HPA059353 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TCEAL8 HPA059115 · Atlas Antibodies	HPA059115 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-DMRTB1 HPA058553 · Atlas Antibodies	HPA058553 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZSCAN25 HPA057173 · Atlas Antibodies	HPA057173 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ONECUT2 HPA057058 · Atlas Antibodies	HPA057058 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TEAD4 HPA056896 · Atlas Antibodies	HPA056896 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF526 HPA056609 · Atlas Antibodies	HPA056609 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-GLIS3 HPA056426 · Atlas Antibodies	HPA056426 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-SALL1 HPA049829 · Atlas Antibodies	HPA049829 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-HMG20B HPA069832 · Atlas Antibodies	HPA069832 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-WDR5 HPA047182 · Atlas Antibodies	HPA047182 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-NELFE HPA046502 · Atlas Antibodies	HPA046502 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ERCC3 HPA046077 · Atlas Antibodies	HPA046077 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-FOXP3 HPA045943 · Atlas Antibodies	HPA045943 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-SOX2 HPA045725 · Atlas Antibodies	HPA045725 Atlas Antibodies	100 µl	£364.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note