Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-PLAG1 HPA072290 · Atlas Antibodies	HPA072290 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TAF1C HPA072229 · Atlas Antibodies	HPA072229 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MED25 HPA068802 · Atlas Antibodies	HPA068802 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-HOXD9 HPA068683 · Atlas Antibodies	HPA068683 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MYC HPA066556 · Atlas Antibodies	HPA066556 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-TAF3 HPA066184 · Atlas Antibodies	HPA066184 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MAZ HPA065930 · Atlas Antibodies	HPA065930 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-VPS72 HPA065709 · Atlas Antibodies	HPA065709 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-RORC HPA065620 · Atlas Antibodies	HPA065620 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF432 HPA065606 · Atlas Antibodies	HPA065606 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZFP91 HPA065325 · Atlas Antibodies	HPA065325 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF444 HPA065203 · Atlas Antibodies	HPA065203 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-KLF3 HPA065054 · Atlas Antibodies	HPA065054 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-GATA6 HPA066629 · Atlas Antibodies	HPA066629 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF34 HPA066805 · Atlas Antibodies	HPA066805 Atlas Antibodies	100 µl	£455.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note