Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-PAX5 HPA068498 · Atlas Antibodies	HPA068498 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF630 HPA068130 · Atlas Antibodies	HPA068130 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TAF5L HPA067941 · Atlas Antibodies	HPA067941 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NR2C1 HPA067767 · Atlas Antibodies	HPA067767 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MBD2 HPA067615 · Atlas Antibodies	HPA067615 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MNT HPA067578 · Atlas Antibodies	HPA067578 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-GMEB2 HPA067455 · Atlas Antibodies	HPA067455 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-FOSL1 HPA066901 · Atlas Antibodies	HPA066901 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-FOXA2 HPA066846 · Atlas Antibodies	HPA066846 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-PKNOX1 HPA065017 · Atlas Antibodies	HPA065017 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF343 HPA052438 · Atlas Antibodies	HPA052438 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZMAT4 HPA069813 · Atlas Antibodies	HPA069813 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NFIC HPA052625 · Atlas Antibodies	HPA052625 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-FOXA1 HPA050505 · Atlas Antibodies	HPA050505 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TBP HPA049805 · Atlas Antibodies	HPA049805 Atlas Antibodies	100 µl	£429.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note