Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-ZNF574 HPA057274 · Atlas Antibodies	HPA057274 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TET1 HPA057273 · Atlas Antibodies	HPA057273 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MXI1 HPA056762 · Atlas Antibodies	HPA056762 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POU3F2 HPA056261 · Atlas Antibodies	HPA056261 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-GTF2A2 HPA056239 · Atlas Antibodies	HPA056239 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-PLAGL1 HPA055706 · Atlas Antibodies	HPA055706 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-LHX4 HPA055705 · Atlas Antibodies	HPA055705 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MYBL2 HPA055416 · Atlas Antibodies	HPA055416 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ATF1 HPA055406 · Atlas Antibodies	HPA055406 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ING1 HPA052591 · Atlas Antibodies	HPA052591 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-E2F3 HPA065012 · Atlas Antibodies	HPA065012 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-BRF1 HPA051918 · Atlas Antibodies	HPA051918 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-E4F1 HPA071325 · Atlas Antibodies	HPA071325 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-THAP1 HPA071310 · Atlas Antibodies	HPA071310 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-HLF HPA071210 · Atlas Antibodies	HPA071210 Atlas Antibodies	100 µl	£455.00 100 µl view

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Download the ChIP-Exo-Seq application note