Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-NCOA1 HPA070520 · Atlas Antibodies	HPA070520 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TCF7 HPA070505 · Atlas Antibodies	HPA070505 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TFCP2 HPA070247 · Atlas Antibodies	HPA070247 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-GTF3C4 HPA069369 · Atlas Antibodies	HPA069369 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POLR3D HPA069089 · Atlas Antibodies	HPA069089 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SOX10 HPA068898 · Atlas Antibodies	HPA068898 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-NFATC1 HPA071732 · Atlas Antibodies	HPA071732 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-HOXC9 HPA072160 · Atlas Antibodies	HPA072160 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NFATC4 HPA076526 · Atlas Antibodies	HPA076526 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-HEY2 HPA074851 · Atlas Antibodies	HPA074851 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF143 HPA074818 · Atlas Antibodies	HPA074818 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ORC2 HPA073881 · Atlas Antibodies	HPA073881 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SNAPC4 HPA073243 · Atlas Antibodies	HPA073243 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-FLI1 HPA073099 · Atlas Antibodies	HPA073099 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF829 HPA073073 · Atlas Antibodies	HPA073073 Atlas Antibodies	100 µl	£455.00 100 µl view

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Download the ChIP-Exo-Seq application note