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Next generation sequencing

Supporting researchers across the NGS workflow

Next Generation Sequencing (NGS) enables comprehensive analysis of genomes, transcriptomes, microbiomes and epigenetic modifications. Successful sequencing projects depend on reliable workflows that take samples from collection through to biological insights.

We supports researchers throughout the NGS workflow with solutions from leading suppliers including Zymo Research, Lexogen and seqWell. While our strongest focus is library preparation, we also offer products and expertise covering sample preservation, nucleic acid extraction, library preparation, sequencing and downstream analysis support. Browse our range below or contact our NGS specialists to get started on your project.

NGS workflow

 

The foundation of any sequencing experiment begins with proper sample collection and preservation. Maintaining nucleic acid integrity during collection and storage is essential to prevent degradation and ensure reliable downstream results. Zymo Research offer DNA/RNA Shield which preserves the genetic integrity and expression profiles of samples at ambient temperatures and completely inactivates infectious agents.

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High-quality nucleic acid extraction is critical for generating reproducible sequencing data. This step removes contaminants while isolating DNA or RNA suitable for sequencing applications.

Zymo Research provides a comprehensive portfolio of DNA and RNA purification kits supporting genomics, transcriptomics, microbiome and epigenetics workflows.

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Library preparation converts extracted nucleic acids into sequencing-ready libraries through processes such as end repair, adapter ligation and amplification. This stage has a major impact on sequencing quality, throughput and overall project success.

We offer specialist solutions from three leading suppliers.

Zymo Research

Zymo Research specialises in epigenenomic and microbiomic library preparation, including whole genome bisulfite sequencing kits, as well as more targeted methylation preparation kits. Their specialised range of microbiome library preparation kits supports both 16S and ITS metagenomic sequencing, with workflows designed to simplify preparation while maintaining robust sequencing performance.

 

metagenomic library prep kits

 

 

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Lexogen

Lexogen specialises in RNA sequencing and transcriptomics, including QuantSeq™ for efficient gene expression profiling and CORALL™ for comprehensive whole-transcriptome RNA sequencing.

 

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seqWell

seqWell focuses on scalable library preparation for high-throughput sequencing applications. Their key technologies include MosaiX™ for short-read whole genome sequencing and hybrid capture workflows, and LongPlex™ for high-multiplex long-read sequencing on PacBio systems. These platforms help researchers scale projects without compromising data quality.

 

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Our featured suppliers provide workflows compatible with leading sequencing platforms. Zymo Research and Lexogen solutions are optimised for Illumina® sequencing workflows, while seqWell LongPlex enables highly multiplexed PacBio HiFi sequencing applications. 

Zymo Resarch and Lexogen both offer end-to-end sequencing service, with Zymo specialising in epigenetic and microbiomic sequencing, and Lexogen in RNA sequencing.

 

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epigenetic services

 

 

RNA sequencing services

 

 

The final stage of the workflow transforms sequencing data into actionable insights, including gene expression measurements, variant identification, microbiome profiling and genome characterisation. This support are available as part of Zymo and Lexogen's sequencing services. Get in touch with our specialists today to get started on your sequencing journey.

 

contact lexogen

 

 

contact zymo