Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-PBRM1 HPA059373 · Atlas Antibodies	HPA059373 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-RBMS2 HPA058784 · Atlas Antibodies	HPA058784 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-GABPB2 HPA058483 · Atlas Antibodies	HPA058483 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-BACH2 HPA058384 · Atlas Antibodies	HPA058384 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-KLF11 HPA058276 · Atlas Antibodies	HPA058276 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-DCP2 HPA057676 · Atlas Antibodies	HPA057676 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ID4 HPA060800 · Atlas Antibodies	HPA060800 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MAFK HPA060841 · Atlas Antibodies	HPA060841 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MLX HPA064438 · Atlas Antibodies	HPA064438 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ATXN7L3 HPA064316 · Atlas Antibodies	HPA064316 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-RXRB HPA063653 · Atlas Antibodies	HPA063653 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TFEC HPA063577 · Atlas Antibodies	HPA063577 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF692 HPA062792 · Atlas Antibodies	HPA062792 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-CEBPB HPA062267 · Atlas Antibodies	HPA062267 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TGIF1 HPA062160 · Atlas Antibodies	HPA062160 Atlas Antibodies	100 µl	£429.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note