Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-PITX1 HPA008743 · Atlas Antibodies	HPA008743 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-FOXJ2 HPA008723 · Atlas Antibodies	HPA008723 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TAF4 HPA008599 · Atlas Antibodies	HPA008599 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NMI HPA008588 · Atlas Antibodies	HPA008588 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SKIL HPA008472 · Atlas Antibodies	HPA008472 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-HMG20A HPA008126 · Atlas Antibodies	HPA008126 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-FOXP4 HPA007176 · Atlas Antibodies	HPA007176 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZSCAN31 HPA007124 · Atlas Antibodies	HPA007124 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MEF2D HPA007114 · Atlas Antibodies	HPA007114 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-PRDM2 HPA005809 · Atlas Antibodies	HPA005809 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-CHD9 HPA049420 · Atlas Antibodies	HPA049420 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TBX5 HPA064683 · Atlas Antibodies	HPA064683 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ELF4 HPA060277 · Atlas Antibodies	HPA060277 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-EHMT2 HPA060259 · Atlas Antibodies	HPA060259 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-HIC2 HPA059399 · Atlas Antibodies	HPA059399 Atlas Antibodies	100 µl	£455.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note