Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-JUNB HPA019149 · Atlas Antibodies	HPA019149 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-SMARCB1 HPA019127 · Atlas Antibodies	HPA019127 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF134 HPA009064 · Atlas Antibodies	HPA009064 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POGZ HPA008781 · Atlas Antibodies	HPA008781 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-DRAP1 HPA006790 · Atlas Antibodies	HPA006790 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-CDK9 HPA006738 · Atlas Antibodies	HPA006738 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TERF2IP HPA006719 · Atlas Antibodies	HPA006719 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF445 HPA006678 · Atlas Antibodies	HPA006678 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZKSCAN1 HPA006672 · Atlas Antibodies	HPA006672 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZSCAN12 HPA006637 · Atlas Antibodies	HPA006637 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TAF6 HPA006566 · Atlas Antibodies	HPA006566 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF18 HPA006144 · Atlas Antibodies	HPA006144 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NFIA HPA006111 · Atlas Antibodies	HPA006111 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-LRRFIP1 HPA006979 · Atlas Antibodies	HPA006979 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MED27 HPA007002 · Atlas Antibodies	HPA007002 Atlas Antibodies	100 µl	£455.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note