Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-ZNF599 HPA014701 · Atlas Antibodies	HPA014701 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-DACH1 HPA012672 · Atlas Antibodies	HPA012672 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-CHD4 HPA012008 · Atlas Antibodies	HPA012008 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-SIRT2 HPA011165 · Atlas Antibodies	HPA011165 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF782 HPA011013 · Atlas Antibodies	HPA011013 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-THRA HPA009654 · Atlas Antibodies	HPA009654 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-FOXK1 HPA018864 · Atlas Antibodies	HPA018864 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NSD3 HPA018893 · Atlas Antibodies	HPA018893 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZFAT HPA020989 · Atlas Antibodies	HPA020989 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF783 HPA020375 · Atlas Antibodies	HPA020375 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF746 HPA020272 · Atlas Antibodies	HPA020272 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-RAD21 HPA020044 · Atlas Antibodies	HPA020044 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TBL1XR1 HPA019182 · Atlas Antibodies	HPA019182 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SMAD4 HPA019154 · Atlas Antibodies	HPA019154 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-CREB1 HPA019150 · Atlas Antibodies	HPA019150 Atlas Antibodies	100 µl	£364.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note