Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-NFIB HPA003956 · Atlas Antibodies	HPA003956 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-SMARCE1 HPA003916 · Atlas Antibodies	HPA003916 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MEIS2 HPA003256 · Atlas Antibodies	HPA003256 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-OLIG2 HPA003254 · Atlas Antibodies	HPA003254 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ELK3 HPA001600 · Atlas Antibodies	HPA001600 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MXD1 HPA001599 · Atlas Antibodies	HPA001599 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-YY1 HPA001119 · Atlas Antibodies	HPA001119 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TAF1 HPA001075 · Atlas Antibodies	HPA001075 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-STAT1 HPA000982 · Atlas Antibodies	HPA000982 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-GTF2A1 HPA000869 · Atlas Antibodies	HPA000869 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-OTX2 HPA000633 · Atlas Antibodies	HPA000633 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ESR1 HPA000450 · Atlas Antibodies	HPA000450 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-ETV6 HPA000264 · Atlas Antibodies	HPA000264 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF148 HPA001656 · Atlas Antibodies	HPA001656 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ELF1 HPA001755 · Atlas Antibodies	HPA001755 Atlas Antibodies	100 µl	£455.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note