Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-MAX HPA003474 · Atlas Antibodies	HPA003474 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZEB2 HPA003456 · Atlas Antibodies	HPA003456 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ATF7 HPA003384 · Atlas Antibodies	HPA003384 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-CUX1 HPA003317 · Atlas Antibodies	HPA003317 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MITF HPA003259 · Atlas Antibodies	HPA003259 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-GABPA HPA003258 · Atlas Antibodies	HPA003258 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-PBX1 HPA003881 · Atlas Antibodies	HPA003881 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-SOX6 HPA003908 · Atlas Antibodies	HPA003908 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MAFB HPA005653 · Atlas Antibodies	HPA005653 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MEF2C HPA005533 · Atlas Antibodies	HPA005533 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MEF2B HPA004734 · Atlas Antibodies	HPA004734 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-HNF4A HPA004712 · Atlas Antibodies	HPA004712 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-TAF10 HPA004148 · Atlas Antibodies	HPA004148 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-CTCF HPA004122 · Atlas Antibodies	HPA004122 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-SMARCD1 HPA004101 · Atlas Antibodies	HPA004101 Atlas Antibodies	100 µl	£455.00 100 µl view

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Download the ChIP-Exo-Seq application note