Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-NR1H3 HPA036443 · Atlas Antibodies	HPA036443 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-FOXO4 HPA040232 · Atlas Antibodies	HPA040232 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF438 HPA039843 · Atlas Antibodies	HPA039843 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF549 HPA039511 · Atlas Antibodies	HPA039511 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POLR3A HPA037926 · Atlas Antibodies	HPA037926 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-RFX6 HPA037696 · Atlas Antibodies	HPA037696 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-USP11 HPA037536 · Atlas Antibodies	HPA037536 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POLR2B HPA037506 · Atlas Antibodies	HPA037506 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZMAT2 HPA036518 · Atlas Antibodies	HPA036518 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POLR3B HPA036466 · Atlas Antibodies	HPA036466 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF674 HPA031026 · Atlas Antibodies	HPA031026 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MLLT10 HPA005747 · Atlas Antibodies	HPA005747 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZFX HPA003877 · Atlas Antibodies	HPA003877 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-FOXP1 HPA003876 · Atlas Antibodies	HPA003876 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-FOXN2 HPA003485 · Atlas Antibodies	HPA003485 Atlas Antibodies	100 µl	£455.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note