- In this section:
- Download the ChIP-Exo-Seq application note
Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.
Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis
How ChIP-Exo-Seq makes a difference
Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays
Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.
Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation
Materials to download
ChIP-Exo-Seq application note
Products
Note: product availability depends on country - see product detail page.
Details | Cat number & supplier | Size | Price |
Anti-NFATC2 HPA024369 · Atlas Antibodies | HPA024369 Atlas Antibodies |
100 µl |
£429.00
100 µl
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Anti-NFKB1 HPA027305 · Atlas Antibodies | HPA027305 Atlas Antibodies |
100 µl |
£364.00
100 µl
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Anti-PRDM10 HPA026997 · Atlas Antibodies | HPA026997 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-SMARCC1 HPA026853 · Atlas Antibodies | HPA026853 Atlas Antibodies |
100 µl |
£429.00
100 µl
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Anti-PRRX2 HPA026808 · Atlas Antibodies | HPA026808 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-GTF2I HPA026638 · Atlas Antibodies | HPA026638 Atlas Antibodies |
100 µl |
£429.00
100 µl
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Anti-TCF4 HPA025958 · Atlas Antibodies | HPA025958 Atlas Antibodies |
100 µl |
£429.00
100 µl
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Anti-ZNF770 HPA024518 · Atlas Antibodies | HPA024518 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-GATAD2A HPA024373 · Atlas Antibodies | HPA024373 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-SUPT3H HPA024371 · Atlas Antibodies | HPA024371 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-ZBTB5 HPA021521 · Atlas Antibodies | HPA021521 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-ZNF354C HPA030904 · Atlas Antibodies | HPA030904 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-ZKSCAN2 HPA049141 · Atlas Antibodies | HPA049141 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-ZNF623 HPA044372 · Atlas Antibodies | HPA044372 Atlas Antibodies |
100 µl |
£455.00
100 µl
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Anti-ZFP69B HPA044289 · Atlas Antibodies | HPA044289 Atlas Antibodies |
100 µl |
£455.00
100 µl
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