Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-RPAP2 HPA046443 · Atlas Antibodies	HPA046443 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF671 HPA046099 · Atlas Antibodies	HPA046099 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POLR2D HPA046092 · Atlas Antibodies	HPA046092 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-KLF5 HPA040398 · Atlas Antibodies	HPA040398 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TOX3 HPA040376 · Atlas Antibodies	HPA040376 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-RFX3 HPA035689 · Atlas Antibodies	HPA035689 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-SFMBT2 HPA035448 · Atlas Antibodies	HPA035448 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF641 HPA035189 · Atlas Antibodies	HPA035189 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF792 HPA035158 · Atlas Antibodies	HPA035158 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TFAP2B HPA034683 · Atlas Antibodies	HPA034683 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-TGIF2LX HPA034543 · Atlas Antibodies	HPA034543 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-LDB1 HPA034488 · Atlas Antibodies	HPA034488 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SIX4 HPA031794 · Atlas Antibodies	HPA031794 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-HSF2 HPA031455 · Atlas Antibodies	HPA031455 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-MED31 HPA035947 · Atlas Antibodies	HPA035947 Atlas Antibodies	100 µl	£455.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note