Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-TADA3 HPA042250 · Atlas Antibodies	HPA042250 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-THAP11 HPA042189 · Atlas Antibodies	HPA042189 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POLR2C HPA041826 · Atlas Antibodies	HPA041826 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-LEUTX HPA041498 · Atlas Antibodies	HPA041498 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-POLR3E HPA041477 · Atlas Antibodies	HPA041477 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-THAP10 HPA041416 · Atlas Antibodies	HPA041416 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-HIF3A HPA041141 · Atlas Antibodies	HPA041141 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SPI1 HPA044653 · Atlas Antibodies	HPA044653 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-POLR2I HPA045156 · Atlas Antibodies	HPA045156 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-INO80C HPA049060 · Atlas Antibodies	HPA049060 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-RFX2 HPA048969 · Atlas Antibodies	HPA048969 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF584 HPA048075 · Atlas Antibodies	HPA048075 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-PATZ1 HPA047893 · Atlas Antibodies	HPA047893 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF239 HPA046679 · Atlas Antibodies	HPA046679 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MECOM HPA046537 · Atlas Antibodies	HPA046537 Atlas Antibodies	100 µl	£429.00 100 µl view

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In this section

Download the ChIP-Exo-Seq application note