Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-ZNF850 HPA029299 · Atlas Antibodies	HPA029299 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-SUPT5H HPA029273 · Atlas Antibodies	HPA029273 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF470 HPA029000 · Atlas Antibodies	HPA029000 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NAB2 HPA027464 · Atlas Antibodies	HPA027464 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZNF277 HPA027307 · Atlas Antibodies	HPA027307 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-NCOA3 HPA024210 · Atlas Antibodies	HPA024210 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-CREB3L1 HPA024069 · Atlas Antibodies	HPA024069 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ARID5A HPA023879 · Atlas Antibodies	HPA023879 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-DMTF1 HPA023846 · Atlas Antibodies	HPA023846 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZSCAN21 HPA023591 · Atlas Antibodies	HPA023591 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ZBTB2 HPA023487 · Atlas Antibodies	HPA023487 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-MLXIP HPA023084 · Atlas Antibodies	HPA023084 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-CHD1 HPA022236 · Atlas Antibodies	HPA022236 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-ATF2 HPA022134 · Atlas Antibodies	HPA022134 Atlas Antibodies	100 µl	£364.00 100 µl view
Anti-ZSCAN2 HPA024331 · Atlas Antibodies	HPA024331 Atlas Antibodies	100 µl	£455.00 100 µl view

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Download the ChIP-Exo-Seq application note