- In this section:
- Download the ChIP-Exo-Seq application note
Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.
Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis
How ChIP-Exo-Seq makes a difference
Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays
Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.
Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation
Materials to download
ChIP-Exo-Seq application note
Products
Note: product availability depends on country - see product detail page.
Details | Cat number & supplier | Size | Price |
Anti-ZNF84 HPA028860 · Atlas Antibodies | HPA028860 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-MTF1 HPA028689 · Atlas Antibodies | HPA028689 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-MED8 HPA028438 · Atlas Antibodies | HPA028438 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-STAT5A HPA027873 · Atlas Antibodies | HPA027873 Atlas Antibodies |
100 µl |
£364.00
100 µl
view
|
Anti-CLOCK HPA027565 · Atlas Antibodies | HPA027565 Atlas Antibodies |
100 µl |
£429.00
100 µl
view
|
Anti-ZEB1 HPA027524 · Atlas Antibodies | HPA027524 Atlas Antibodies |
100 µl |
£429.00
100 µl
view
|
Anti-FOXK2 HPA027523 · Atlas Antibodies | HPA027523 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-TAF4B HPA028937 · Atlas Antibodies | HPA028937 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-ZNF514 HPA028974 · Atlas Antibodies | HPA028974 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-ZNF30 HPA030400 · Atlas Antibodies | HPA030400 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-ZNF25 HPA030190 · Atlas Antibodies | HPA030190 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-ATF5 HPA030187 · Atlas Antibodies | HPA030187 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-SOX4 HPA029901 · Atlas Antibodies | HPA029901 Atlas Antibodies |
100 µl |
£429.00
100 µl
view
|
Anti-ZNF426 HPA029342 · Atlas Antibodies | HPA029342 Atlas Antibodies |
100 µl |
£455.00
100 µl
view
|
Anti-NRF1 HPA029329 · Atlas Antibodies | HPA029329 Atlas Antibodies |
100 µl |
£429.00
100 µl
view
|