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Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
Anti-ZNF84 HPA028860 · Atlas Antibodies
HPA028860
Atlas Antibodies
100 µl £455.00
100 µl
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Anti-MTF1 HPA028689 · Atlas Antibodies
HPA028689
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-MED8 HPA028438 · Atlas Antibodies
HPA028438
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-STAT5A HPA027873 · Atlas Antibodies
HPA027873
Atlas Antibodies
100 µl £364.00
100 µl
view
Anti-CLOCK HPA027565 · Atlas Antibodies
HPA027565
Atlas Antibodies
100 µl £429.00
100 µl
view
Anti-ZEB1 HPA027524 · Atlas Antibodies
HPA027524
Atlas Antibodies
100 µl £429.00
100 µl
view
Anti-FOXK2 HPA027523 · Atlas Antibodies
HPA027523
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-TAF4B HPA028937 · Atlas Antibodies
HPA028937
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-ZNF514 HPA028974 · Atlas Antibodies
HPA028974
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-ZNF30 HPA030400 · Atlas Antibodies
HPA030400
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-ZNF25 HPA030190 · Atlas Antibodies
HPA030190
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-ATF5 HPA030187 · Atlas Antibodies
HPA030187
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-SOX4 HPA029901 · Atlas Antibodies
HPA029901
Atlas Antibodies
100 µl £429.00
100 µl
view
Anti-ZNF426 HPA029342 · Atlas Antibodies
HPA029342
Atlas Antibodies
100 µl £455.00
100 µl
view
Anti-NRF1 HPA029329 · Atlas Antibodies
HPA029329
Atlas Antibodies
100 µl £429.00
100 µl
view