Antibodies for immuno-oncology research

Bethyl Laboratories offers a range of highly validated antibodies for the identification of immune cells, tumour cells and checkpoint inhibitors during tumour microenvironment profiling. Including the new PD-L1 recombinant rabbit monoclonal antibody, this range of antibodies is ideal for the determination of immune cells and immunosuppressive signals within the tumour microenvironment.

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Benefits of using these antibodies
• Highly validated antibodies
• Highly validated for IHC, WB and IF
• Validation data available
• Recombinant rabbit monoclonal antibodies available
• Trial sizes available
• Protected by Cambridge Bioscience Antibody Guarantee

New PD-L1 recombinant rabbit monoclonal antibody is eight times more sensitive then leading competitor

The leading competitor's rabbit anti-PD-L1 monoclonal antibody was compared against Bethyl's new PD-L1 recombinant rabbit monoclonal antibody [BLR020E] (A700-020) in accordance to each manufacturer's protocol as stated on the product datasheet, which seeks to optimise antibody performance. Bethyl’s PD-L1 recombinant rabbit monoclonal antibody was proved to be eight times more sensitive.

Detection of human PD-L1 (red) and Lamin-A/C (green) in FFPE tonsil by IHC-IF. Antibody: Rabbit anti-PD-L1 recombinant monoclonal [BLR020E] (A700-020) and rabbit anti-Lamin-A/C (A303-430A). Secondary: DyLight® 594-conjugated goat anti-rabbit IgG (A120-201D4) and DyLight® 488-conjugated goat anti-rabbit IgG (A120-201D2). Counterstain: DAPI (blue)

Detection of human CD45 in FFPE small intestine by IHC. Antibody: Rabbit anti-CD45 recombinant monoclonal [BL-178-12C7] (A700-012). Secondary: HRP-conjugated goat anti-rabbit IgG (A120-501P). Substrate: DAB.

Applications
• Tumour microenvironment profiling
• Immunohistochemistry
• Western blotting
• Immunofluorescence

Below is a small selection of immuno-oncology antibodies available. For a full list please contact our Bethyl Laboratories Specialist Here.