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Antibodies for immuno-oncology research

Bethyl Laboratories offers a range of highly validated antibodies for the identification of immune cells, tumour cells and checkpoint inhibitors during tumour microenvironment profiling. Including the new PD-L1 recombinant rabbit monoclonal antibody, this range of antibodies is ideal for the determination of immune cells and immunosuppressive signals within the tumour microenvironment.

Benefits of using these antibodies
• Highly validated antibodies
• Highly validated for IHC, WB and IF
• Validation data available
• Recombinant rabbit monoclonal antibodies available
• Trial sizes available
• Protected by Cambridge Bioscience Success Guarantee

New PD-L1 recombinant rabbit monoclonal antibody is eight times more sensitive then leading competitor

PD-L1 Comparison

The leading competitor's rabbit anti-PD-L1 monoclonal antibody was compared against Bethyl's new PD-L1 recombinant rabbit monoclonal antibody [BLR020E] (A700-020) in accordance to each manufacturer's protocol as stated on the product datasheet, which seeks to optimise antibody performance. Bethyl’s PD-L1 recombinant rabbit monoclonal antibody was proved to be eight times more sensitive.

PD-L1 and CD45 detection

Left: Detection of human PD-L1 (red) and Lamin-A/C (green) in FFPE tonsil by IHC-IF. Antibody: Rabbit anti-PD-L1 recombinant monoclonal [BLR020E] (A700-020) and rabbit anti-Lamin-A/C (A303-430A). Secondary: DyLight® 594-conjugated goat anti-rabbit IgG (A120-201D4) and DyLight® 488-conjugated goat anti-rabbit IgG (A120-201D2). Counterstain: DAPI (blue). Right: Detection of human CD45 in FFPE small intestine by IHC. Antibody: Rabbit anti-CD45 recombinant monoclonal [BL-178-12C7] (A700-012). Secondary: HRP-conjugated goat anti-rabbit IgG (A120-501P). Substrate: DAB.

Applications
• Tumour microenvironment profiling
• Immuno oncology research
• Immunohistochemistry
• Western blotting
• Immunofluorescence

Material available for download
T-cell profiling paper

Below is a small selection of immuno-oncology antibodies available. For a full list please contact our Bethyl Laboratories Specialist Here.

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
Mouse anti-CD20 Monoclonal Antibody, Purified [L26] A500-017A · Bethyl Laboratories, Inc.
A500-017A
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
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Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1] A500-020A · Bethyl Laboratories, Inc.
A500-020A
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
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Mouse anti-CD8 alpha Monoclonal Antibody, Purified [C8/144B] A500-021A · Bethyl Laboratories, Inc.
A500-021A
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
view
Rabbit anti-CD45 Recombinant Monoclonal Antibody [BL-178-12C7] A700-012 · Bethyl Laboratories, Inc.
A700-012
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
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Rabbit anti-CD45 Recombinant Monoclonal Antibody [BL-178-12C7] A700-012-T · Bethyl Laboratories, Inc.
A700-012-T
Bethyl Laboratories, Inc.
10 µl (5+ tests) £128.00
10 µl (5+ tests)
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Rabbit anti-CD4 Recombinant Monoclonal Antibody [BL-155-1C11] A700-015 · Bethyl Laboratories, Inc.
A700-015
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
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Rabbit anti-CD247/CD3Z Recombinant Monoclonal Antibody [BL-336-1B2] A700-017 · Bethyl Laboratories, Inc.
A700-017
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
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Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E] A700-022 · Bethyl Laboratories, Inc.
A700-022
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
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Rabbit anti-CD86 Recombinant Monoclonal Antibody [BLR029F] A700-029 · Bethyl Laboratories, Inc.
A700-029
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
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Rabbit anti-CD86 Recombinant Monoclonal Antibody [BLR030F] A700-030 · Bethyl Laboratories, Inc.
A700-030
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
view
Rabbit anti-IDO1 Recombinant Monoclonal Antibody [BLR031F] A700-031 · Bethyl Laboratories, Inc.
A700-031
Bethyl Laboratories, Inc.
100 µl (50+ tests) £485.00
100 µl (50+ tests)
view