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Cell lines for drug discovery

BPS Bioscience provide stable cell lines expressing validated surface proteins, engineered to enable several research applications, such as CAR-T modelling, inhibitor/activator studies, pathway analysis and high-throughput screening systems.

Benefits of using BPS Bioscience cell lines
• >200 stable cell lines
• Vigorously tested
• Carefully selected
• Custom cell reporter systems available

Available cell line formats:

Cell line format Uses
Reporter cell lines •    Test activation or inhibition of a cellular pathway using high throughput screening
•    Measure signalling, promoter and transcription factor activities
•    >20 available cell lines
•    >70 available reporter systems
Co-stimulatory cell lines •    Inhibitor screening
•    Antibody affinity
•    Co-culture studies
Overexpression/knockout cell lines •    Screen antibodies or compounds against a given gene
•    Available for ion channel studies, GPCR screens, and metabolite-based assays
•    Varying expression levels to mimic different stages of cancer target cells
CAR-T reporter cell lines •    CAR engineering optimisation
•    Compound/Ab screening
•    CAR-T signaling research
•    Screening donor variations


All BPS Bioscience cell lines have been extensively validated, confirming biological activity when appropriate. Detailed protocols are included with instructions for general cell culture and maintenance. Each cell line is tested for viability and mycoplasma prior to shipping, ensuring valid and reproducible results while minimising the need for end-user optimisation and troubleshooting. 

Custom cell line development
With their cell line development services, BPS Bioscience can engineer cell lines with a knocked-out protein, stably expressing proteins at high, homogenous levels, or bearing reporter constructs.

Materials for download:
BPS cell systems brochure

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
BCMA CHO Recombinant Cell Line (High Expression) BPS-79500-H · BPS Bioscience
BPS-79500-H
BPS Bioscience
2 vials £6894.00
2 vials
view
SLAMF7 (CS1) CHO Recombinant Cell Line (High Expression) BPS-79608-H · BPS Bioscience
BPS-79608-H
BPS Bioscience
2 vials £7239.00
2 vials
view
CD37/CHO Recombinant Cell Line (High Expression) BPS-79607-H · BPS Bioscience
BPS-79607-H
BPS Bioscience
2 vials £6894.00
2 vials
view
CD47 - HEK293 Cell Line BPS-71249 · BPS Bioscience
BPS-71249
BPS Bioscience
2 vials £7372.00
2 vials
view
PD-L1 - CHO Recombinant Cell Line BPS-60543 · BPS Bioscience
BPS-60543
BPS Bioscience
2 vials £5521.00
2 vials
view
CD20 CHO Recombinant Cell Line (High Expression) BPS-79624-H · BPS Bioscience
BPS-79624-H
BPS Bioscience
2 vials £7584.00
2 vials
view
ROR1-CHO Recombinant Cell Line BPS-79609-H · BPS Bioscience
BPS-79609-H
BPS Bioscience
2 vials £7966.00
2 vials
view
CD38 CHO Recombinant Cell Line (High Expression) BPS-79615-H · BPS Bioscience
BPS-79615-H
BPS Bioscience
2 vials £7584.00
2 vials
view
BCMA CHO Recombinant Cell Line (Low Expression) BPS-79500-L · BPS Bioscience
BPS-79500-L
BPS Bioscience
2 vials £6894.00
2 vials
view
HER2 (ERBB2) CHO Recombinant Cell Line (Low Expression) BPS-79612-L · BPS Bioscience
BPS-79612-L
BPS Bioscience
2 vials £7584.00
2 vials
view
CD19 CHO Recombinant Cell Line (Medium Expression) BPS-79561-M · BPS Bioscience
BPS-79561-M
BPS Bioscience
2 vials £7584.00
2 vials
view
CD19 CHO Recombinant Cell Line (Low Expression) BPS-79561-L · BPS Bioscience
BPS-79561-L
BPS Bioscience
2 vials £7584.00
2 vials
view
CD22 CHO Recombinant Cell Line (High Expression) BPS-79557-H · BPS Bioscience
BPS-79557-H
BPS Bioscience
2 vials £7584.00
2 vials
view
CD19 CHO Recombinant Cell Line (High Expression) BPS-79561-H · BPS Bioscience
BPS-79561-H
BPS Bioscience
2 vials £7584.00
2 vials
view
HER2 (ERBB2) CHO Recombinant Cell Line (Medium Expression) BPS-79612-M · BPS Bioscience
BPS-79612-M
BPS Bioscience
2 vials £7584.00
2 vials
view