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Small molecule drug discovery solutions

Accelerate your small molecule drug discovery with cutting-edge kinase assays from AssayQuant and high-quality cell lines from BPS Bioscience. Together, these advanced tools empower researchers to identify and optimise lead candidates with greater efficiency while reducing time to market.

Small molecule drug discovery banner

Why do BPS Bioscience cell lines and AssayQuant kinase assays work well together?

Our advanced kinase assays from AssayQuant and expertly-engineered cell lines from BPS Bioscience create a powerful synergy for small molecule drug discovery. AssayQuant’s real-time, fluorescence-based kinase assays provide precise, quantitative measurements of kinase activity, enabling rapid screening and optimisation of potential inhibitors. Once promising compounds are identified, BPS Bioscience’s high-quality cell lines allow researchers to validate their effects in a biologically relevant context. This seamless workflow - from in vitro biochemical assays to cellular validation - enhances data reliability, accelerates lead optimisation, and improves the chances of developing effective, selective small molecule therapeutics.

Read more about how you can leverage this integrated workflow including robust early-stage screening and biologically relevant validation for your own research.

Why choose BPS Bioscience for your cellular validation needs?

These cell lines provide a reliable and reproducible platform for studying drug-target interactions, pathway modulation, and cellular responses in a biologically relevant context. By using BPS Bioscience’s stable cell lines expressing specific kinases, receptors, or signaling proteins, researchers can accurately validate compound efficacy, selectivity, and toxicity.

Benefits of using BPS cell lines

  • Validate your lead at an accurate, cellular level
  • Trust your data with extensively tested cell lines
  • Custom cell lines available

Why choose AssayQuant for your inhibitory activity screening needs?

Our kinase assays from kinetics experts AssayQuant offer a highly sensitive and efficient solution for screening inhibitory activity in small molecule drug discovery. Their real-time, fluorescence-based technology enables continuous kinetic monitoring, providing deeper insights into inhibitor binding, potency, and mechanism of action. Designed for high-throughput screening, these assays allow rapid and precise identification of potent kinase inhibitors with minimal background interference.

Benefits of using AssayQuant kinase assays

  • Observe your reaction in real-time
  • Detect actual phosphorylation & dephosphorylation
  • Eliminate the need for antibody reagents, coupling procedures & radioisotope labeling
     

Materials to download
Cell systems brochure
AssayQuant tech brochure

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
GIPR/CRE Luciferase Reporter HEK293 Cell Line BPS-78589 · BPS Bioscience
BPS-78589
BPS Bioscience
2 vials £13005.00
2 vials
view
CIITA Knockout THP-1 Cell Line BPS-78390 · BPS Bioscience
BPS-78390
BPS Bioscience
2 vials £6915.00
2 vials
view
B2M/CIITA Double Knockout THP-1 Cell Line BPS-78391 · BPS Bioscience
BPS-78391
BPS Bioscience
2 vials £10106.00
2 vials
view
Cas9/GFP Safe-Harbor HEK293 Cell Line BPS-78582 · BPS Bioscience
BPS-78582
BPS Bioscience
2 vials £1570.00
2 vials
view
TCR Knockout NFAT-Luciferase Reporter Jurkat Cell Line BPS-78556 · BPS Bioscience
BPS-78556
BPS Bioscience
2 vials £13632.00
2 vials
view
TCR/B2M Knockout NFAT Luciferase Reporter Jurkat Cell Line BPS-78557 · BPS Bioscience
BPS-78557
BPS Bioscience
2 vials £16872.00
2 vials
view
GLP-1R/CRE Luciferase Reporter HEK293 Cell Line BPS-78176 · BPS Bioscience
BPS-78176
BPS Bioscience
2 vials £12228.00
2 vials
view
CRISPRa (SAM) HEK293 Cell Line BPS-78192 · BPS Bioscience
BPS-78192
BPS Bioscience
2 vials £2862.00
2 vials
view
CRISPRa (SAM) HeLa Cell Line BPS-78193 · BPS Bioscience
BPS-78193
BPS Bioscience
2 vials £2527.00
2 vials
view
CRISPRa (SAM) HepG2 Cell Line BPS-78194 · BPS Bioscience
BPS-78194
BPS Bioscience
2 vials £2660.00
2 vials
view
Anti-CD19 CAR / NFAT (Luciferase) Reporter Jurkat Cell Line (CD19 SCFV-CD28-4-1BB-CD3ΞΆ) BPS-79853 · BPS Bioscience
BPS-79853
BPS Bioscience
2 vials £11000.00
2 vials
view
Anti-CD19 CAR negative control/ NFAT (Luciferase) Reporter Jurkat Cell Line (CD19 SCFV-CD28 transmembrane motif) BPS-79854 · BPS Bioscience
BPS-79854
BPS Bioscience
2 vials £2623.00
2 vials
view
Cas9 Expressing Jurkat Cell Pool BPS-78070 · BPS Bioscience
BPS-78070
BPS Bioscience
2 vials £846.00
2 vials
view
Cas9 Expressing A549 Cell Pool BPS-78072 · BPS Bioscience
BPS-78072
BPS Bioscience
2 vials £846.00
2 vials
view
CRISPRa (SAM) Jurkat Cell Line BPS-78080 · BPS Bioscience
BPS-78080
BPS Bioscience
2 vials £2660.00
2 vials
view