Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
3510.2
Product Description:
This Abeta peptide (11-40) is FAM-labeled (Abs/Em=494/521 nm). FAM is preferred over FITC because of its photo- and chemical stability.
Post-mortem Alzheimer’s diseased brain specimens reveal significant levels of Aβ (11-40/42) within insoluble amyloid pools. The β-secretase enzyme or β-amyloid precursor protein-cleaving enzyme (BACE) generates the N terminus of Aβ, ultimately leading to the production of full-length Aβ (1-40/42) or truncated Aβ (11-40/42). The abundance of Aβ (11-40/42) produced by BACE suggests that their roles in AD pathogenesis may be important.
Storage Temperature:
-20°C Darkness