This proteinase activated receptor (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to it's varied cellular effects of thrombin, PAR-1 also has been shown to co-ordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.
Proteins & Peptides
Peak Area by HPLC ≥95%
1, Kauffmann, R. et al. Oncol. Rep. 21:1261-1267 (2009). 2, Kirilak, YA. et al. Intl. J. Mol. Med. 17:551-558 (2006).