This is amino acids 54 to 65 fragment of sulfated hirudin, a 65-residue peptide. Hirudin is found in the saliva of the leech Hirudo medicinalis. This sulfated peptide binds tightly to anion-binding exosite I of thrombin, but does not inhibit hydrolysis of synthetic peptide substrates. Non-sulfated Hirudin (54-65) is cat# 62987.
Proteins & Peptides
Peak Area by HPLC ≥95%
Van Deerlin, V. et al. J. Biol. Chem. 266, 20223 (1997).