This tumor antigenic peptide presented by HLA-A2 antigen to CTLs, is a tyrosinase fragment. Tyrosinase is a membrane-bound protein involved in the melanin synthesis pathway that is expressed by virtually all primary melanoma lesions and by most of metastatic lesions.
Proteins & Peptides
Peak Area by HPLC ≥95%
Chapiro, J. et al. J. Immunol. 176, 1053 (2006); Paczesny, S. et al. JEM 199, 1503 (2004); Lee, P. et al J. Clin. Oncol. 19, 3836 (2001).