HIF-1 {alpha} (556-574)
Supplier:
Catalogue number:
ANA61528
Size:
1 mg
Product is available in:
This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process
Product Type:
Proteins & Peptides
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
2254.6
Reference:
Ref: Hirsilä, M. et al. J Biol. Chem 278, 30772 (2003); Robinson, B. Pediatric Research 50, 673 (2001).
UNSPSC Code:
12352202
Sorry - there are no images available for this product.