£143.00
Estimated delivery Thu 16 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
762.9
- Data sheet: View or download
Product Description:
Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This protease-activated receptor-1 (PAR-1) selective peptide induces cyclooxygenase-2 (COX-2) protein and mRNA expression in human endothelial cells. Studies show that intratracheal instillation of the PAR1-specific peptide increases lung edema during high-tidal-volume ventilation