Methylation status is an important epigenetic marker. Modifications such as 5-methylcytosine and 5-hydroxymethylcytosine play important roles in gene regulation, development, and genomic stability. These can be analysed by bisulfite conversion on a whole genome level or in a more targeted way using reduced representation methods. Our bisulfite conversion kits are supplied by Zymo Research and involve gentle bisulfite conversion that converts >99.5% of non-methylated cytosines and protects >99.5% of unmethylated cytosines.
