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Small molecule drug discovery solutions

Accelerate your small molecule drug discovery with cutting-edge kinase assays from AssayQuant and high-quality cell lines from BPS Bioscience. Together, these advanced tools empower researchers to identify and optimise lead candidates with greater efficiency while reducing time to market.

Small molecule drug discovery banner

Why do BPS Bioscience cell lines and AssayQuant kinase assays work well together?

Our advanced kinase assays from AssayQuant and expertly-engineered cell lines from BPS Bioscience create a powerful synergy for small molecule drug discovery. AssayQuant’s real-time, fluorescence-based kinase assays provide precise, quantitative measurements of kinase activity, enabling rapid screening and optimisation of potential inhibitors. Once promising compounds are identified, BPS Bioscience’s high-quality cell lines allow researchers to validate their effects in a biologically relevant context. This seamless workflow - from in vitro biochemical assays to cellular validation - enhances data reliability, accelerates lead optimisation, and improves the chances of developing effective, selective small molecule therapeutics.

Read more about how you can leverage this integrated workflow including robust early-stage screening and biologically relevant validation for your own research.

Why choose BPS Bioscience for your cellular validation needs?

These cell lines provide a reliable and reproducible platform for studying drug-target interactions, pathway modulation, and cellular responses in a biologically relevant context. By using BPS Bioscience’s stable cell lines expressing specific kinases, receptors, or signaling proteins, researchers can accurately validate compound efficacy, selectivity, and toxicity.

Benefits of using BPS cell lines

  • Validate your lead at an accurate, cellular level
  • Trust your data with extensively tested cell lines
  • Custom cell lines available

Why choose AssayQuant for your inhibitory activity screening needs?

Our kinase assays from kinetics experts AssayQuant offer a highly sensitive and efficient solution for screening inhibitory activity in small molecule drug discovery. Their real-time, fluorescence-based technology enables continuous kinetic monitoring, providing deeper insights into inhibitor binding, potency, and mechanism of action. Designed for high-throughput screening, these assays allow rapid and precise identification of potent kinase inhibitors with minimal background interference.

Benefits of using AssayQuant kinase assays

  • Observe your reaction in real-time
  • Detect actual phosphorylation & dephosphorylation
  • Eliminate the need for antibody reagents, coupling procedures & radioisotope labeling
     

Materials to download
Cell systems brochure
AssayQuant tech brochure

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
B2M Knockout NFAT Luciferase Reporter Jurkat Cell Line BPS-78363 · BPS Bioscience
BPS-78363
BPS Bioscience
2 vials £11803.00
2 vials
view
B2M Knockout THP-1 Cell Line BPS-78389 · BPS Bioscience
BPS-78389
BPS Bioscience
2 vials £6915.00
2 vials
view
Anti-BCMA CAR /NFAT (Luciferase) Reporter Jurkat Cell Line BPS-79694 · BPS Bioscience
BPS-79694
BPS Bioscience
2 vials £10000.00
2 vials
view
Cas9 Inducible (Tet-On) iPS Cell Pool BPS-78845 · BPS Bioscience
BPS-78845
BPS Bioscience
1 vial £9096.00
1 vial
view
B2M Knockout iPS Cell Line BPS-82161 · BPS Bioscience
BPS-82161
BPS Bioscience
1 vial £7431.00
1 vial
view
Transduction Control (Tet-On) iPS Cell Pool BPS-82289 · BPS Bioscience
BPS-82289
BPS Bioscience
2 vials £2500.00
2 vials
view
BCMA Knockout RPMI-8226 Cell Line BPS-82659 · BPS Bioscience
BPS-82659
BPS Bioscience
2 vials £5851.00
2 vials
view
BCMA Knockout MM.1S Cell Line BPS-82687 · BPS Bioscience
BPS-82687
BPS Bioscience
2 vials £5851.00
2 vials
view
PhosphoSens-Kinetic Kinase Discovery Kit (AKT1, AKT2, AKT3, SGK1, SGK2, SGK3) KT-AQT0536K · AssayQuant Technologies Inc
KT-AQT0536K
AssayQuant Technologies Inc
1 discovery kit £340.00
1 discovery kit
view
PhosphoSens-Kinetic Kinase Discovery Kit (ABL1 [E255K], ABL1 [E255V], ABL1 [H396P], ABL1 [Q252H], ABL1 [T315I], ABL1 [Y253F], ABL1 [Y253H], ABL1, ABL2) KT-AQT0032K · AssayQuant Technologies Inc
KT-AQT0032K
AssayQuant Technologies Inc
1 discovery kit £340.00
1 discovery kit
view
PhosphoSens-Kinetic Kinase Discovery Kit (ALK [G1202R], ALK [L1196M/G1202R], ALK, AXL, BLK, BMX, CSF1R, CSK, ERBB2 [A775/G776insYVMA], ERBB2, ERBB4, FER, FES, FGFR1, FGFR2, FGFR3 [V555M], FGFR3, FGFR4, FLT1, FLT3, FLT4, FRK, FYN (FYNa), FYN (FYNb), HCK, I KT-AQT0794K · AssayQuant Technologies Inc
KT-AQT0794K
AssayQuant Technologies Inc
1 discovery kit £340.00
1 discovery kit
view
PhosphoSens-Kinetic Kinase Discovery Kit (ALK [T1151-L1152insT], ALK [C1156Y], ALK [F1174L], ALK [G1269A], ALK [L1196M], ALK [R1275Q], ALK, BTK [C481S], BTK, FGFR3 [G697C], FGFR3 [K650E], FGFR3 [K650M], FGFR3 [V555L], ITK, ROS1 [G2032R]) KT-AQT0101K · AssayQuant Technologies Inc
KT-AQT0101K
AssayQuant Technologies Inc
1 discovery kit £340.00
1 discovery kit
view
PhosphoSens-Kinetic Kinase Discovery Kit (AURKA, AURKB [G160L], AURKB, AURKC, PRKX) KT-AQT0186K · AssayQuant Technologies Inc
KT-AQT0186K
AssayQuant Technologies Inc
1 discovery kit £340.00
1 discovery kit
view
PhosphoSens-Kinetic Kinase Discovery Kit (BCR, EPHA2, EPHA3, EPHA4, EPHB1, EPHB2, EPHB3, EPHB4, FGR, INSRR, JAK2 (JH1), JAK2 (JH1JH2), JAK3 (JH1), KIT, PDGFRA, PDGFRB, PTK2B, RET, ROS1) KT-AQT0661K · AssayQuant Technologies Inc
KT-AQT0661K
AssayQuant Technologies Inc
1 discovery kit £340.00
1 discovery kit
view
PhosphoSens-Kinetic Kinase Discovery Kit (BRAF [V600E]) KT-AQT0682K · AssayQuant Technologies Inc
KT-AQT0682K
AssayQuant Technologies Inc
1 discovery kit £340.00
1 discovery kit
view