Seeing off-target effects dominate results with conventional RNAi reagents, siTOOLs Biotech (co-founded in 2013) decided to test the concept of complex but defined siRNA pools to “dilute” off-target effects and increase knock down specificity. This lead to the development of the siPOOL technology which has been used by a growing number of researchers from both academic and industry labs to study gene function in a broad range of experimental setups.
Following a similar pooling approach but towards biotinylated DNA probes and to support the growing use of next-generation sequencing, riboPOOLs were developed as an efficient, affordable ribosomal RNA depletion solution that could be applied towards any species.
Cambridge Bioscience is pleased to distribute siTOOLs Biotech in UK & Ireland.
