Beta-Amyloid (1-16), Human - ANA24226 - 5 mg - AnaSpec - proteins & peptides
Beta-Amyloid (1-16), Human
Catalogue number:
ANA24226
Name:
Beta-Amyloid (1-16), Human
Supplier:
Availability:
Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Aβ (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aβ in senile plaque of Alzheimer’s disease with Aβ (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aβ and free radical damage.
Data sheet:
Product Type:
Proteins & Peptides
Alternative Names:
DAEFRHDSGYEVHHQK
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
1955
Reference:
Da Silva, GFZ. et al. J. Biol. Chem. 280, 16601 (2005); Kowalik-Jankowska, T. et al. J. Inorg. Biochem. 98, 940 (2004); Kowalik-Jankowska, T. et al. J. Inorg. Biochem. 95, 270 (2003).
UNSPSC Code:
12352202
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