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Beta-Amyloid (1-16), Human

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Catalogue number:
ANA24225
Size:
1 mg
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Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Aβ(1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aβ in senile plaque of Alzheimer’s disease with Aβ (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aβ and free radical damage.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

1955

Reference:

Da Silva, GFZ. et al. J. Biol. Chem. 280, 16601 (2005); Kowalik-Jankowska, T. et al. J. Inorg. Biochem. 98, 940 (2004); Kowalik-Jankowska, T. et al. J. Inorg. Biochem. 95, 270 (2003).

UNSPSC Code:

12352202

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