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Beta-Amyloid (1-28), Human - ANA24231 - 0.5 mg - AnaSpec - proteins & peptides

Beta-Amyloid (1-28), Human
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Size: 0.5 mg
£137.00
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Catalogue number:
ANA24231
Name:
Beta-Amyloid (1-28), Human
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The three-dimensional solution structure of Aß (1-28) reveals the folding of the peptide to form a predominantly a-helical structure with a bend centered at residue 12 and the side chains of histidine-13 and lysine-16 in close proximity, residing on the same face of the helix. Their proximity may constitute a binding motif with the heparan sulfate proteoglycans. Aß (1-28) is highly hydrophilic and shares sequences with bA4, the major component of Aß. Its assembly is fibrillar, i.e., elongated in a single direction. Reports show that synthetic peptides Aß (1-40) and Aß (1-28) have significant effects on normal human plasma cholesterol esterification rate. Both peptides (at concentration of 1 ng/mL) inhibit plasma cholesterol esterification rate by 40-50% compared to the control value.

Data sheet:

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Product Type:
Proteins & Peptides
Alternative Names:
DAEFRHDSGYEVHHQKLVFFAEDVGSNK
Storage Temp:
-20°C
Molecular Weight:
3262.5
Reference:
Kirshenbaum K. and V. Daggett, Biochem. 34, 7640 (1995); Talafous, J. et al. Biochem. 33, 7788 (1994).
UNSPSC Code:
12352202