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Sinomenine Hydrochloride

Supplier:
Catalogue number:
s3353-1 g
Size:
1 g
Product is available in:
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£53.00 Estimated delivery Tue 5 Oct
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Alkaloid found in Sinomenium; acid-sensing ion channel and L-type Ca2+ channel blocker.

Product Type:

Biochemicals

CAS Number:

6080-33-7

Storage Temp:

4°C

Compound Purity:

≥98%

Molecular Weight:

365.86

Reference:

Li X, Wang K, Ren Y, et al. MAPK signaling mediates sinomenine hydrochloride-induced human breast cancer cell death via both reactive oxygen species-dependent and -independent pathways: an in vitro and in vivo study. Cell Death Dis. 2014 Jul 31;5:e1356. PMID: 25077542. Zhang MY, Li P, Wang DQ, et al. Analgesic effect of sinomenine on SSNI model rats and monoamine neurotransmitters in striatal extracellular fluid. Zhongguo Zhong Yao Za Zhi. 2013 Feb;38(4):597-604. PMID: 23713290. Chen Z, Tao Z, Zhang N, et al. The role of sinomenine in treatment of allergic rhinitis mice model and its mechanism. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Jan;27(2):81-4. PMID: 23650707. Oh YC, Kang OH, Kim SB, et al. Anti-inflammatory effect of sinomenine by inhibition of pro-inflammatory mediators in PMA plus A23187-stimulated HMC-1 Cells. Eur Rev Med Pharmacol Sci. 2012 Sep;16(9):1184-91. PMID: 23047501. Wu WN, Wu PF, Chen XL, et al. Sinomenine protects against ischaemic brain injury: involvement of co-inhibition of acid-sensing ion channel 1a and L-type calcium channels. Br J Pharmacol. 2011 Nov;164(5):1445-59. PMID: 21585344.

Structure:

C19H23NO4 HCl

Formula:

C19H23NO4 HCl

UNSPSC Code:

12352200

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