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Tacrolimus

Supplier:
Catalogue number:
t0008-100 mg
Size:
100 mg
Product is available in:
  • UK
  • Ireland
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£545.00 Estimated delivery Tue 5 Oct
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Calcineurin inhibitor.

Product Type:

Biochemicals

CAS Number:

104987-11-3

Alternative Names:

FK-506, Fujimycin, Prograf, Protopic, CCRIS 7124.

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

804.02

Reference:

Carr WW. Topical calcineurin inhibitors for atopic dermatitis: review and treatment recommendations. Paediatr Drugs. 2013 Aug;15(4):303-10. PMID: 23549982. Manojlovic Z, Blackmon J, Stefanovic B. Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis. PLoS One. 2013 Jun 3;8(6):e65897. PMID: 23755290. Grigoriu S, Bond R, Cossio P, et al. The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin. PLoS Biol. 2013;11(2):e1001492. PMID: 23468591. Shin JH, Park HR, Kim SW, et al. The effect of topical FK506 (tacrolimus) in a mouse model of allergic rhinitis. Am J Rhinol Allergy. 2012 Mar-Apr;26(2):e71-5. PMID: 22487280. Izumi S, Nozaki Y, Komori T, et al. Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17beta-glucuronide, estrone-3-sulfate, and sulfobromophthalein. Drug Metab Dispos. 2013 Oct;41(10):1859-1866. PMID: 23920221.

Structure:

C44H69NO12

Formula:

C44H69NO12

UNSPSC Code:

12352200

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