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Simvastatin

Supplier:
Catalogue number:
s3449-10 mg
Size:
10 mg
Product is available in:
  • UK
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  • Europe
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£57.00 Estimated delivery Tue 28 Sep
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Statin; HMG-CoA reductase inhibitor, potential ATP-sensitive K+ channel activator, L-type Ca2+ channel blocker.

Product Type:

Biochemicals

CAS Number:

79902-63-9

Alternative Names:

Synvinolin, MK-733, Denan, Liponorm, Lodales, Simovil, Sinvacor, Sivastin, Zocor, Zocord

Storage Temp:

Ambient

Compound Purity:

≥97%

Molecular Weight:

418.57

Reference:

Zhou J, Li W, Xie Q, et al. Effects of simvastatin on glucose metabolism in mouse MIN6 cells. J Diabetes Res. 2014;2014:376570. PMID: 24995341. Banach M, Czuczwar SJ, Borowicz KK. Statins - are they anticonvulsant? Pharmacol Rep. 2014 Aug;66(4):521-8. PMID: 24948050. Wang Q, Wei X, Gao H, et al. Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: the association with improvements in long-term memory. Neuroscience. 2014 May 16;267:57-66. PMID: 24613723. Yang N, Cui Y, Tan J, et al. Local injection of a single dose of simvastatin augments osteoporotic bone mass in ovariectomized rats. J Bone Miner Metab. 2014 May;32(3):252-60. PMID: 23934055. Ishikawa S, Hayashi H, Kinoshita K, et al. Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer. Int J Cancer. 2013 Dec 17. [Epub ahead of print]. PMID: 24346863. Moraes LA, Vaiyapuri S, Sasikumar P, et al. Antithrombotic actions of statins involve PECAM-1 signaling. Blood. 2013 Oct 31;122(18):3188-96. PMID: 24030383. Liu PY, Liu YW, Lin LJ, et al. Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation. Circulation. 2009 Jan 6;119(1):131-8. PMID: 19075102.

Structure:

C25H38O5

Formula:

C25H38O5

UNSPSC Code:

12352200

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