Quality control studies of microbiomics research suggest that the workflow is littered with potential sources of error and bias. From collection to sequencing, the potential for variation at each step in the microbiomics workflow is enormous.
ZymoBIOMICS Microbial Community Standards citations
The microbial community standards from Zymo Research allow scientists to validate and standardise their methods and have confidence in their results.
Detecting bias in the microbiomic workflow
Standards available
ZymoBIOMICS™ standards |
Microbial Community Standard |
Microbial Community Standard II |
Spike in control |
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Formats
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Microbial cell
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Isolated DNA
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Microbial cells
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Isolated DNA
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High microbial load
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Low microbial load
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Detect bias in
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Complete workflow and DNA extraction
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Library prep and sequencing
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Complete workflow and DNA extraction
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Library prep and sequencing
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Complete workflow and DNA extraction
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Complete workflow and DNA extraction
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Recommended use
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General benchmarking and microbiome profiling positive control
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Assess detection limit and sensitivity
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Absolute quantification of high bacterial load samples e.g. faeces
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Absolute quantification of low bacterial load samples e.g. sputum
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For long read library prep and sequencing, a high molecular weight DNA standard is available. This isolated DNA standard can be used as a positive control for general benchmarking and microbiome profiling.
Microbiomics & metagenomics portfolio
Cambridge Bioscience offers a comprehensive solution for microbiomic and metagenomic research from collection to analyses. See the full range.