GSK3368715 (dihydrochloride)
Catalogue number:
HY-128717A-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1628925-77-8
Purity:
99.96
Molecular Formula:
C20H40Cl2N4O2
Molecular Weight:
439.46
Mass Spectrometry:
Reference Materials
Alternative Names:
EPZ019997 (dihydrochloride)
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- MSDS: View or download
- Protocol: View or download
Product Description:
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity[1].
