Sotorasib
Catalogue number:
HY-114277-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2296729-00-3
Purity:
99.90
Molecular Formula:
C30H30F2N6O3
Molecular Weight:
560.59
Mass Spectrometry:
Reference Materials
Alternative Names:
AMG-510
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C‑mutated locally advanced or metastatic non‑small cell lung cancer (NSCLC)[1][2][3][4][5][6].
