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CAS Number:
1051375-19-9
Purity:
99.96%
Molecular Formula:
C20H18F2N3NaO5
Molecular Weight:
441.36
Alternative Names:
S/GSK1349572 sodium
- Data sheet: View or download
- MSDS: View or download
Product Description:
Dolutegravir sodium (S/GSK1349572 sodium) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir sodium (S/GSK1349572 sodium) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir sodium (S/GSK1349572 sodium) retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM).
