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S Opsin Antibody

Catalogue number:
600-101-MP7
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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Applications:

ELISA, Immunohistochemistry

Antibody Host:

Goat

Species Reactivity:

Mus musculus (Mouse)

Antibody Isotype:

IgG

Antibody Type:

Polyclonal

Immunogen:

Anti-S Opsin antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal por

Alternative Names:

Goat Anti-Short-wave-sensitive opsin 1 Antibody, S opsin, Blue cone photoreceptor pigment, Blue-sensitive opsin, BOP, Short wavelength-sensitive cone opsin, Bcp, Opn1sw

Product Description:

Short-wave-sensitive opsin 1 belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors. Involved in ensuring correct abundance and localization of retinal membrane proteins. May increase spectral sensitivity in dim light. Defects in this gene are the cause of tritan color blindness (tritanopia) . Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. Anti-S Ospin Antibody is useful for researchers interested in Color Blindness, Metabolism of fat-soluble vitamins, and Peptide ligand-binding receptors. Anti-S Ospin Antibody has been tested in ELISA and IHC. Expect a band at ~39kDa in western blot using appropriate tissues and lysates. Positive control used: Mouse eye tissue in Immunohistochemistry.

Immunohistochemistry of Goat Anti-S Opsi
Immunohistochemistry of Goat Anti-S Opsin Antibody. Tissue: Mouse Eye Tissue (retina). Antigen Retrieval: HIER using Citrate buffer for 20mins. Fixative: none. Primary Antibody: Anti-S Ospin at 1:100 for 30 mins at RT. Secondary Antibody: Donkey Anti-Goat HRP at 4µL/mL for 20mins at RT. Counterstain: Hematoxylin. Analysis Results: S opsin is expected to stain the outer rod cells of the retina, which it does at a dilution of 1:100.