Autophagy ELISA Kit (LC3-II Quantitation)

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CBA-5116

Supplier:

Cell Biolabs

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96 assays

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£762.00

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Estimated delivery Wed 18 Feb
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Autophagy ELISA Kit (LC3-II Quantitation) - 96 assays

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Processing of LC3. During autophagy, pro — Processing of LC3. During autophagy, pro-LC3 undergoes C-terminal proteolysis to form LC3-I (Cytosolic). LC3-I protein conjugates to phosphatidylethanolamine (PE) and translocates to the autophagosomal membrane (LC3-II). A selective permeabilization procedure is utilized to remove cytosolic pro-LC3 /LC3-I and retain autophagosome-bound LC3-II. LC3-II is used as a specific marker of autophagy.